It is made use of being an analgesic (agony reliever) present in prescription drugs by yourself or in combination with other medicinal components such as acetaminophen or acetylsalicylic acid.

Never share promethazine/phenylephrine/codeine with Others, even when they've a similar situation when you. It may harm them.

Even though considerably less popular, quite possibly the most significant Uncomfortable side effects of promethazine/phenylephrine/codeine are described under, along with what to do if they materialize.

Send out Prescriptions Add prescriptions by means of online account or send out them through alternative methods. Entry prescription historical past for long term refills.

In the case of the toddler death, the mother was located to generally be a CYP2D6 ultra-rapid metabolizer, which most likely resulted in larger amounts of morphine secreted in to the breast milk bringing about the infant’s Loss of life.

) Paradoxical Reactions- Hyperexcitability and irregular movements have been claimed in clients pursuing a single administration of promethazine HCl. Consideration ought to be given for the discontinuation of promethazine HCl and to the usage of other medication if these reactions take place. Respiratory depression, nightmares, delirium, and agitated actions have also been claimed in Some clients.

Codeine phosphate is an opioid check here analgesic with employs much like Individuals of morphine, but is much less potent being an analgesic. Its Principal web site of motion is in the mu

The chronic usage of opioids, together with codeine sulfate, may perhaps produce obstructive bowel disorder, particularly in people with fundamental disorders of intestinal motility Label. Outcomes on the central anxious procedure

出血性大腸炎の患者。（重篤な細菌性下痢、腸管出血性大腸菌や赤痢菌等の患者では、症状の悪化、治療期間の延長を生じる可能性がある）

The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric people a lot less than 6 several years of age, since The mix may possibly trigger lethal respiratory depression Within this age populace.

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Codeine functions right over the central nervous program and lessens inner thoughts of pain by interrupting the way in which nerves signal agony amongst the Mind and your body.

This medication could possibly be pattern-forming. In the event you feel that the medicine is not really Performing as well, tend not to use more than your prescribed dose. Call your medical professional for Directions.

Promethazine is well absorbed from the gastrointestinal tract. Clinical effects are apparent inside 20 minutes following oral administration and generally last 4 to 6 several hours, Even though They might persist provided that twelve hrs. Promethazine is metabolized with the liver to a range of compounds; the sulfoxides of promethazine and N-demethylpromethazine are classified as the predominant metabolites showing from the urine.